Khloe is the youngest Kardashian sister and appears alongside her other family members on Keeping Up With the Kardashians. She and her sisters' lives were nearly brought to a tragic end when a reader of the controversial novel The Poop That Took a Pee attempted to gun them down, but they were resurrected under mysterious circumstances. She's been known to stop by Unplanned Parenthood for off-the-record abortions, and is one of Martin Poonlover's least favorite patients.
- The Tale of Scrotie McBoogerballs (s14e02)
During the level at Unplanned Parenthood, one of her abortions, purported to be the largest in the clinic's history, mutates into a Giant Nazi Zombie Baby, and the player must defeat them in an epic boss battle, as well as their evil umbilical chord. Khloe herself does not appear.